Governance

Biotie Therapies Corp. is a public Finnish limited liability company which complies with the Finnish Companies Act, Securities Market Act, Accounting Act, the rules of NASDAQ OMX Helsinki Ltd as well as the Company’s Articles of Association. In addition, Biotie complies with the Finnish Corporate Governance Code

The Company departs from the recommendations of the Code as follows:
- in deviation from recommendation 43 of the Code, member of the Board of Directors Guido Magni holds options entitling to shares in the Company. The options relate to Synosia Therapeutics Holding AG’s option program and were granted prior to the acquisition of Synosia Therapeutics Holding AG by Biotie.

Corporate Governance principles

-------------------------
March 25, 2011
The Corporate Governance Statement 2010 is presented as a separate report and was disclosed together with the financial statements and the report by the Board of Directors.

The Corporate Governance Statement 2009 is presented as a separate report and was disclosed together with the financial statements and the report by the Board of Directors.

------------------------

Updated March 25, 2011